Baker’s yeast isn’t just useful in the kitchen — it may also be built for space. Researchers found that yeast cells can survive intense shock waves and toxic chemicals similar to those on Mars. The cells protect themselves by forming special stress-response structures that help them endure extreme c…
A giant virus discovered in Japan is adding fuel to the provocative idea that viruses helped create complex life. Named ushikuvirus, it infects amoebae and shows unique traits that connect different families of giant DNA viruses. Its unusual way of hijacking and disrupting the host cell’s nucleus of…
Researchers are engineering bacteria to invade tumors and consume them from the inside. Because tumor cores lack oxygen, they’re the perfect breeding ground for these microbes. The team added a genetic tweak that helps the bacteria survive longer near oxygen-exposed edges — but only once enough of t…
Scientists have built a massive cellular atlas showing how aging reshapes the body across 21 organs. Studying nearly 7 million cells, they found that aging starts earlier than expected and unfolds in a coordinated way throughout the body. About a quarter of cell types change in number over time, and many of these shifts differ between males and females. The research also highlights shared genetic “hotspots” that could become targets for anti-aging therapies.
A famously resilient bacterium may be tough enough to survive one of the most violent events imaginable on Mars. In laboratory experiments designed to mimic the crushing shock of a massive asteroid impact, researchers squeezed Deinococcus radiodurans between steel plates and blasted it with pressure…
Researchers have revealed how bacteria precisely control the genes that trigger cell division. The study shows that the MraZ protein, which normally forms a donut-shaped structure, must bend and partially break apart to bind key DNA sequences that activate division genes. Using cryo-electron microsc…
The FDA's concerns, which the agency raised with Fulcrum executives at a recent end-of-phase meeting, stemmed from an unexpectedly high rate of secondary blood cancers seen with another PRC2 inhibitor—Ipsen’s Tazverik® (tazemetostat), indicated to treat follicular lymphoma and epithelioid sarcoma, the company disclosed, based on meeting minutes received May 28. The post Fulcrum Halts Development of SCD Candidate Pociredir, Sets Strategic Review appeared first on GEN - Genetic Engineering and Biotechnology News.
Australian regulators clear Scribe Therapeutics to begin testing a one-time CRISPR therapy designed to lower “bad” cholesterol for years. Cardiovascular disease remains the world’s biggest killer, yet one of its main drivers – elevated LDL cholesterol – is often treated with therapies people must ta…
